Dataset
Publications
Genome-Wide Association Study of Circadian Rhythmicity in 71,500 UK Biobank Participants and Polygenic Association With Mood Instability.
Ferguson A, et al.
EBioMedicine 2018 Sep;35:279-287. doi: 10.1016/j.ebiom.2018.08.004.
PMID:30120083
Dataset phenotypes
- Low relative amplitude cases vs controls
- Relative amplitude
Dataset subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 77,440 | UK Biobank | European |
Experiment summary
This study analyzed genetic associations with relative amplitude, a measure of circadian rhythm derived from accelerometer data of UK Biobank participants. Two analyses were performed: a case-control analysis (2,700 cases, 68,300 controls) of low relative analysis as a dichotomous trait (displayed in the Portal as the phenotype "Low relative amplitude cases vs controls"); and an analysis of relative amplitude as a continuous trait (displayed in the Portal as the phenotype "Relative amplitude").
Sex-stratified subsets of this dataset are also available in the Portal.