T1DGC 2015 ImmunoChip: European ancestry

Publications

Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers.
Onengut-Gumuscu S, et al.
Nat Genet. 2015 Apr;47(4):381-6. doi: 10.1038/ng.3245.
PMID:25751624

Phenotypes

  • Type 1 diabetes

Subjects

Cases Controls Cohort Ancestry
6,670 0 UK GRID European
0 6,523 British 1958 Birth Cohort European
0 2,893 UK National Blood Services collection European
0 2,846 NIHR Cambridge Biomedical Research Centre Cambridge BioResource European

Project

The Type 1 Diabetes Genetics Consortium was formed to investigate the genetic basis of type 1 diabetes and to make genetic data available to the T1D research community.

Experiment summary

In this study a new genotyping array, the ImmunoChip, was designed in order to identify genetic loci associated with risk of T1D. This dataset includes genetic associations for T1D from more than 6,600 T1D cases and over 12,000 controls.

Dataset ID
GWAS_T1DGC_IChipMETA2015