The Association to Function Knowledge Portal (A2FKP) project has three major aims:
- Aggregate high quality datasets and bioinformatic methods for 11 classes of disease
- Integrate data and methods from each community within a comprehensive resource
- Develop programmatic and web-based interfaces for accessing the resource
The A2FKP is supported by funding from the National Human Genome Research Institute and is being developed by a team of scientists and software engineers at the Broad Institute, the European Bioinformatics Institute, the University of California at San Diego, the University of Michigan, and many other collaborators from academia, industry, and non-profit organizations worldwide.
- Contact the team to make suggestions or get individual help
- Interested in collaborating or contributing data to the Portal? Read our guide to data submission.
Knowledge Portal and Data Coordinating Center (DCC) team
| Project directors | Noël Burtt Jason Flannick |
| Creative lead | Maria Costanzo |
| Software engineers | Marc Duby Drew Hite Quy Hoang Dong-Keun Jang Annie Moriondo Oliver Ruebenacker Alex Shilin Patrick Smadbeck
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| Computational biologists | Ryan Koesterer Fahrisa Islam Maisha Trang Nguyen |
| Project managers | MacKenzie Brandes Phebe Olorunfemi |
Common Metabolic Diseases Genome Atlas
| Principal Investigator | Kyle Gaulton |
| Parul Kudtarkar Ying Sun |
University of Michigan
| Principal Investigator | Michael Boehnke |
| Alan Kwong Laura Scott Ryan Welch |
European Bioinformatics Institute
| Principal Investigator | Thomas Keane |
| Aoife McMahon Yue Ji |
Community Portal Collaborators
| Aging | Daniel Evans |
| Cardiovascular system | Jonathan Rosand Jin-Moo Lee Patrick Ellinor Thomas Lumbers Pradeep Natarajan Gina Peloso Krishna Aragam Scott Demour Steven Lubitz |
| Endocrine system | Jose Flores Inês Barroso Josep Mercader |
| Growth and Development/Obesity | Ruth Loos Karen Mohlke Joel Hirschhorn |
| Immune System | Christopher Cotsapas Timothy Vyse Steven Rich |
| Musculoskeletal system | Douglas Kiel Eleftheria Zeggini Bani Hosseini Iris Fischer Will Rayner |
| Nervous system | Sali Farhan Mike Nalls, on behalf of GP2 and CARD Richa Saxena Michael Weedon |
| Renal system | Nora Franceschini Anna Köttgen Katalin Susztak |
| Reproductive system | John Perry |
| Respiratory system | Michael Cho Benjamin Raby |
| Sensory system | John Paul SanGiovanni Maryam Zekavat Nazlee Zebardast Elizabeth Rossin Jay Wang |
