Join the Knowledge Portal Community!

We are interested in forming collaborations around new data, methods, and tools. We encourage researchers to contact us about new data relevant to the genetics of type 1 and 2 diabetes, cardiovascular disease, stroke, sleep and circadian disorders, and related traits. We also welcome collaboration on development of general methods and tools for analysis and presentation of genetic association data for complex diseases and traits.
Find instructions on how to submit summary statistics here.

Some frequently asked questions:

Why should I contribute my data?

  • See your data in the context of hundreds of thousands of samples.
  • Have your data analyzed and checked by the expert Analysis Team at the AMP Data Coordinating Center (AMP-DCC).
  • Get access to cutting edge analysis tools that can be used for your research.
  • Share your data with the wider research community. See FAQs on data management and sharing here here.
  • Fulfill NIH requirements to make your data available in an NIH-supported scientific data repository.

What kind of data do we need?

  • Right now, we are ready to receive array, exome sequencing, and whole-genome sequencing genetic association data, and credible sets. We are interested in incorporating both summary statistics and individual-level data. You can find submission instructions here.
  • We are also interested in incorporating gene expression, eQTL, chromatin accessibility, and epigenetic data, and the results of computational methods. Most of these data types are first incorporated into the Common Metabolic Diseases Genome Atlas (CMDGA) and then annotations generated from specific data types are incorporated into the Knowledge Portals. You can find instructions on submitting data to CMDGA here.

What compliance/regulatory documents are needed to submit individual-level data to the Common Metabolic Diseases Knowledge Portal?

  • In order to include individual-level data in the CMDKP, you will need to obtain permission from your institution's IRB review board (or your country's equivalent) to share the data with us and make summary level metrics available on the Portal.
  • We also ask that you sign a Data Transfer Agreement.

What will we do with your data?

  • For individual-level data, we will perform quality control and association analysis in order to generate summary-level data for display on the Portal.
  • All data types submitted to the Portal are included in multiple bioinformatic analyses.
  • You will have the opportunity to review the results before any data are made available on the Portal.

How will we protect your data?

  • Only summary level analysis will be displayed on the portal. We will never show individual level data.
  • We have analyzed the privacy risks inherent in sharing summary statistics in the Knowledge Portals and found them to be extremely low. Read our white paper here.
  • Click here to learn more about our policies on data transfer, use, and protection.

What if your data can’t come to the United States?

  • A Federated Node at EMBL-EBI allows data to be stored there and be accessed by the Portal. In the future, we plan to release technology that will support additional federated nodes in other locations.

Data Submission Questions

Contact our data intake team at:
amp-dcc-data-submission@broadinstitute.org

General Questions

Contact us

Summary Statistic Submissions

Submission instructions

Submitting Genomic Data to CMDGA

CMDGA data types and formats