MSK-KP Downloads

GWAS Summary Statistic Downloads

Other Data Downloads

GWAS Summary Statistic Downloads

Dataset name in MSK-KP Publication Download
(Dataset not yet incorporated into MSK-KP) Genome-wide meta-analysis of muscle weakness identifies 15 susceptibility loci in older men and women.
Jones G, et al.
Nat Commun. 2021 Jan 28;12(1):654. doi: 10.1038/s41467-021-20918-w.
PMID:33510174
Download (GWAS Catalog)
Bone size GWAS GWAS of bone size yields twelve loci that also affect height, BMD, osteoarthritis or fractures.
Styrkarsdottir U, et al.
Nat Commun. 2019 May 3;10(1):2054. doi: 10.1038/s41467-019-09860-0.
PMID:31053729
Download (GEFOS)
GEFOS eBMD and Fracture GWAS An atlas of genetic influences on osteoporosis in humans and mice.
Morris JA, et al.
Nat Genet 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x.
PMID:30598549
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UK Biobank-arcOGEN osteoarthritis GWAS Meta-analysis Identification of New Therapeutic Targets for Osteoarthritis Through Genome-Wide Analyses of UK Biobank Data.
Tachmazidou I, et al.
Nat Genet. 2019 Feb; 51(2): 230–236. doi: 10.1038/s41588-018-0327-1
PMID:30664745
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GEFOS Any-type of Fracture GWAS Assessment of the genetic and clinical determinants of fracture risk: genome wide association and mendelian randomisation study.
Trajanoska K, et al.
BMJ. 2018 Aug 29;362:k3225. doi: 10.1136/bmj.k3225.
PMID:30158200
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Life-course total body BMD GWAS Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Medina-Gomez C, et al.
Am J Hum Genet. 2018 Jan 4; 102(1): 88–102. doi: 10.1016/j.ajhg.2017.12.005
PMID:29304378
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UK Biobank eBMD GWAS Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis.
Kemp JP, Morris JA, Medina-Gomez Cet al.
Nat Genet. 2017 Oct; 49(10): 1468–1475. doi: 10.1038/ng.3949
PMID:28869591
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Pediatric musculoskeletal traits GWAS Bivariate genome-wide association meta-analysis of pediatric musculoskeletal traits reveals pleiotropic effects at the SREBF1/TOM1L2 locus.
Medina-Gomez C, et al.
Nat Commun. 2017; 8: 121.doi: 10.1038/s41467-017-00108-3
PMID:28743860
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Lean body mass GWAS Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.
Zillikens MC, et al.
Nat Commun. 2017 Jul 19;8(1):80. doi: 10.1038/s41467-017-00031-7.
PMID:28724990
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UK10K BMD GWAS Whole-genome sequencing identifies EN1 as a determinant of bone density and fracture.
Zheng H-F, et al.
Nature. 2015 Oct 1;526(7571):112-7. doi: 10.1038/nature14878.
PMID:26367794
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GEFOS LS- FN- BMD(2) GWAS Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture.
Estrada K, et al.
Nat Genet. 2012 Apr 15;44(5):491-501. doi: 10.1038/ng.2249.
PMID:22504420
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Other Data Downloads

Publication Downloads
A molecular quantitative trait locus map for osteoarthritis.
Steinberg J, et al.
Nat Commun. 2021; 12: 1309. doi: 10.1038/s41467-021-21593-7
PMID:33637762
eQTLs, low-grade cartilage
eQTLs, high-grade cartilage
eQTLs, synovium
pQTLs, low-grade cartilage
pQTLs, high-grade cartilage
Differential gene expression and differential protein abundance, high-grade vs. low-grade cartilage