MEDIA T2D GWAS

Publications

Meta-analysis of genome-wide association studies in African Americans provides insights into the genetic architecture of type 2 diabetes.
Ng MC, et al.
PLoS Genet. 2014 Aug 7;10(8):e1004517. doi: 10.1371/journal.pgen.1004517.

Dataset phenotypes

  • type 2 diabetes

Dataset subjects

Cases Controls Cohort (Click to view selection criteria for cases and controls) Ancestry
955 414 Atherosclerosis Risk in Communities Study (ARIC) African American
94 654 Coronary Artery Risk Development in Young Adults (CARDIA) African American
81 98 Cleveland Family Study (CFS) African American
226 474 Cardiovascular Health Study (CHS) African American
146 322 Family Heart Study (FamHS) African American
228 620 Genetic Study of Atherosclerosis Risk (GeneSTAR) African American
293 246 Genetic Epidemiology Network of Arteriopathy (GENOA) African American
104 664 Healthy Aging in Neighborhoods of Diversity across the Life Span Study (HANDLS) African American
382 232 Health, Aging, and Body Composition Study (Health ABC) African American
183 738 Howard University Family Study (HUFS) African American
333 1,450 Jackson Heart Study (JHS) African American
411 793 Multi-Ethnic Study of Atherosclerosis (MESA) African American
69 551 MESA Family Study (MESA Family) African American
1,141 1,243 Sea Islands Genetic Network - Reasons for Geographic And Racial Differences in Stroke (SIGNET-REGARDS) African American
1,674 801 Wake Forest School of Medicine, 
Family Investigation of Nephropathy in Diabetes (WFSM_FIND) African American
1,964 6,243 Women's Health Initiative (WHI) African American

Experiment summary

The MEDIA T2D GWAS, from the MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium, is a meta-analysis of 17 studies comprising 8,284 T2D cases and 15,543 controls, all of African American ancestry.

Dataset ID
GWAS_MEDIA_aa