CKDGen GWAS - microalbuminuria associations

Dataset

All CKDGen GWAS datasets draw upon overlapping sample sets.

Download summary statistics

Publications

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Teumer A, et al.
Nat Commun. 2019 Sep 11;10(1):4130. doi: 10.1038/s41467-019-11576-0

Dataset phenotypes

  • microalbuminuria

Dataset subjects

Samples Cohort Ancestry
2,919 Action in Diabetes and Vascular disease : preterAx and diamicroN mr Controlled Evaluation (ADVANCE) European
2,784 Age, Gene/Environment Susceptibility Study (AGES) European
1,739 Atherosclerosis Risk in Communities study (ARIC) African American
5,976 Atherosclerosis Risk in Communities study (ARIC) European
3,598 The Cooperative Health Research in South Tyrol (CHRIS) European
368 Cardiovascular Health Study (CHS) African American
1,524 Cardiovascular Health Study (CHS) European
5,146 deCODE genetics/Amgen (DECODE) European
1,113 DIAbetes COhoRtE (DIACORE) European
1,740 Epidemiological investigation of the chances of preventing, recognizing early and optimally treating chronic diseases in an elderly population (ESTHER) European
5,288 The Framingham Heart Study (FHS) European
3,998 German Chronic Kidney Disease study (GCKD) European
1,207 Jackson Heart Study (JHS) African American
2,084 Cooperative Health Research in the Augsburg Region (KORA F3) European
2,320 Cooperative Health Research in the Augsburg Region (KORA F4) European
3,989 LIFE-Adult (LIFE-Adult) European
1,454 LIFE-Child (LIFE-Child) European
11,766 Lifelines Cohort Study (Lifelines) European
1,286 Multi-Ethnic Study of Atherosclerosis (MESA) African American
2,065 Multi-Ethnic Study of Atherosclerosis (MESA) European
1,146 Multi-Ethnic Study of Atherosclerosis (MESA) Hispanic
9,908 MyCode Community Health Initiative (MyCode (Geisinger Research)) European
5,258 Netherlands Epidemiology of Obesity (NEO) European
2,639 Prevention of Renal and Vascular End-stage Disease study (PREVEND) European
2,558 Rotterdam Study (RS-III) European
1,430 Singapore Chinese Eye Study(SCES)-610 (SCES) East Asian
2,345 Study of Health in Pomerania (SHIP) European
985 Study of Health in Pomerania - Trend (SHIP-Trend) European
431 Singapore Malay Eye Study (SiMES) East Asian
1,442 Singapore Indian Eye Study (SINDI) South Asian
855 Singapore Prospective Study Program (SP2) East Asian
256,402 UK (United Kingdom) Biobank (UKBB) European
198 Vanderbilt BioVU (Vanderbilt-660) European
293 Vanderbilt BioVU (Vanderbilt-Omni1) European

Project

Chronic Kidney Disease Genetics Consortium (CKDGen)

CKDGen is a consortium of researchers investigating genetic loci associated with kidney function and disease.

Experiment summary

Summary meta-analysis data are provided for urinary albumin-to-creatinine ratio. Unless otherwise specified, analyses were performed among participants of European ancestry. Analyses were performed on the entire group except for those indicated to include only participants with or without T2D.

Dataset ID
GWAS_CKDGenConsortiumMA