Dataset
Publications
Seven New Loci Associated With Age-Related Macular Degeneration.
Fritsche LG, et al.
Nat Genet. 2013 Apr; 45(4): 433–439e2.
PMID:23455636
Dataset phenotypes
- Age-related macular degeneration
- Neovascular age-related macular degeneration
- Geographic atrophy
Dataset subjects
| Cases | Controls | Cohort | Ancestry |
|---|---|---|---|
| 963 | 4,262 | AMD-Europe-Johns Hopkins University(AMD-EU-JHU) | European |
| 103 | 1,052 | Blue Mountains Eye Study (BMES) | European |
| 721 | 33,463 | deCODE AMD | European |
| 317 | 1,636 | Frankonian AMD study/Kooperative Gesundheitsforschung in der Region Augsburg Study (FAS/KORA) | European |
| 827 | 3,323 | Japanese Age Related Eye Disease Study (JAREDS) | East Asian |
| 71 | 76 | Massachusetts Eye and Ear Institute (MEEI) Sibpairs | European |
| 49 | 49 | Melbourne AMD GWAS | European |
| 867 | 689 | Miami/Vanderbilt | |
| 1,464 | 1,150 | Michigan/Mayo Clinic/AREDS/UPENN (MMAP) | |
| 192 | 1,887 | Rotterdam Study | European |
| 912 | 1,679 | Tufts Medical Center/Massachusetts General Hospital (Tufts/MGH) | European |
| 161 | 260 | UCSD GA Study | |
| 150 | 601 | UK Cambridge/Edinburgh Study 300k platform | European |
| 743 | 1,598 | UK Cambridge/Edinburgh Study 550k platform | European |
| 110 | 119 | Vision Research Foundation (VRF, India) | South Asian |
Project
The International Age-related Macular Degeneration Genomics Consortium (originally the AMD Gene Consortium) was formed in early 2010 by 18 research groups from across the world, with support from the National Eye Institute, in order to analyze the genetic architecture of age-related macular degeneration.
Experiment summary
IAMDGC 2013 AMD GWAS is a meta-analysis combining data for >7,600 age-related macular degeneration (AMD) cases with advanced disease (geographic atrophy, neovascularization, or both) and >50,000 controls.
Dataset ID
GWAS_AMDGen