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Publications
Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis.
Choi SH, et al.
Circ Genom Precis Med. 2021 Aug;14(4):e003300. doi: 10.1161/CIRCGEN.120.003300.
PMID: 34319147
Phenotypes
- PR interval
- P-wave duration
- QRS interval
- Corrected QT interval (QTc)
- RR interval
Project
The NHLBI Trans-Omics for Precision Medicine program (TOPMed) integrates whole-genome sequencing with other 'omics data to improve scientific understanding of heart, lung, blood, and sleep disorders.
Experiment summary
This study analyzed genetic associations with five electrocardiographic traits in 28,008 subjects from the TOPMed cohort.
Dataset ID
Choi2021_ECGtraits_Mixed