Data submission, use, and access
The Cardiovascular Disease Knowledge Portal will serve as the gateway to a large and growing aggregation of data relevant to the genetics of cardiovascular disease and its complications, along with analyses, tools, and visualizations to interpret those data.
The Broad Institute will aggregate data, support analyses, and continue to update capabilities to disseminate results relevant to the genetics of cardiovascular disease and related traits, while coordinating collaboration within the Portal.
Individual-level data will never be shared with CVDKP users. Individual-level data will reside in one or several data vaults behind a secure firewall. User-activated modules will be deployed behind the firewall to analyze the data or query precomputed results. The purpose of the CVDKP is to enable broad access to genetic information concerning cardiovascular disease in a form that meets user needs while maintaining individual privacy requirements. CVDKP users are encouraged to provide feedback on the extent to which the CVDKP meets those goals.
Portal Access and Terms of Conduct
Data use and availability
All users are welcome to use results from analyses of these data to further their research without seeking explicit permission from the Portal team or funders.
User Responsibilities
Portal users are expected to abide by the following provisions on data use:
- Users will not attempt to download any dataset in bulk from the Portal, other than those made available for public download
- Users will not attempt to identify or contact research participants
- Users will protect data confidentiality
- Users will not share any of the data with unauthorized users
- Users will report any inadvertent data release, security breach, or other data management incidents of which they become aware
- Users will abide by all applicable laws and regulations for handling genomic data
Agreeing to these provisions is a requirement of Portal use. Violating them may result in an NIH investigation and sanctions including revocation of access to the Portal.
Citing portal data
Users are welcome to cite the CVDKP in scientific publications. Please cite both the website and the CVDKP publication. If users are citing a single dataset represented in the CVDKP, they should cite both the CVDKP and the relevant paper for that dataset.
Cite the website as follows:
Cardiovascular Disease Knowledge Portal (broadcvdi.org). Year Month Date of access; URL of page you are citing (RRID:SCR_016536).
Also cite this publication:
Costanzo MC, Roselli C, Brandes M, Duby M, Hoang Q, Jang D, Koesterer R, Kudtarkar P, Moriondo A, Nguyen T, Ruebenacker O, Smadbeck P, Sun Y, Butterworth AS, Aragam KG, Thomas Lumbers R, Khera AV, Lubitz SA, Ellinor PT, Gaulton KJ, Flannick J, Burtt NP. Cardiovascular Disease Knowledge Portal: A Community Resource for Cardiovascular Disease Research. Circ Genom Precis Med. 2023 Oct 10:e004181. doi: 10.1161/CIRCGEN.123.004181. Epub ahead of print. PMID: 37814896.