ISGC early-onset ischemic stroke 2022 GWAS: trans-ancestry

Download summary statistics:

Trans-ancestry results:
Early-onset ischemic stroke
TOAST cardio-aortic embolism
TOAST large artery atherosclerosis
TOAST small artery occlusion
TOAST other determined
TOAST other undetermined

European ancestry results:
Early-onset ischemic stroke
TOAST cardio-aortic embolism
TOAST large artery atherosclerosis
TOAST small artery occlusion
TOAST other determined
TOAST other undetermined

README

Publications

Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.
Jaworek T, et al.
Neurology. 2022 Oct 17;99(16):e1738-e1754. doi: 10.1212/WNL.0000000000201006.
PMID: 36240095 

Phenotypes

• Early onset ischemic stroke
• TOAST cardio-aortic embolism
• TOAST large artery atherosclerosis
• TOAST small artery occlusion
• TOAST other determined
• TOAST other undetermined

Experiment summary

This study was a trans-ancestry analysis of genetic associations for early-onset ischemic stroke and its sub-types in up to 16,730 cases and 599,237 controls.