Publication
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Trubetskoy V, Pardiñas AF, Qi T, et al.
Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5.
PMID: 35396580
Phenotypes
- Schizophrenia
Experiment summary
This mixed ancestry GWAS analyzed 74776 schizophrenia cases and 101023 controls, identifying associated loci and implicating genes expressed in excitatory and inhibitory neurons; fine-mapping and integrative analyses prioritized candidate genes and pathways.
Dataset ID
Trubetskoy2022_SCZ_Mixed