EXTEND GWAS

Dataset

Cases in the EXTEND GWAS dataset are included in the ExTexT2D exome chip analysis dataset.

Phenotypes

  • Alanine transaminase
  • Alkaline phosphatase
  • Bilirubin
  • Blood urea nitrogen
  • BMI
  • Body fat percentage
  • Diastolic blood pressure
  • eGFR-creat (serum creatinine)
  • HbA1c (mmol per L)
  • HDL cholesterol
  • Height
  • Hip circumference
  • Potassium
  • Ratio total to HDL cholesterol
  • Sodium
  • Systolic blood pressure
  • Total cholesterol
  • Triglycerides
  • Urinary albumin
  • Urinary albumin-to-creatinine ratio
  • Urinary creatinine
  • Waist circumference
  • Weight

Subjects

Cases Controls Cohort Ancestry
1,395 5,764 EXTEND European

Project

The Exeter EXTEND Biobank recruits adults over age 18 living within a 25-mile radius of Exeter, UK. The population is comprised of approximately 20% diabetics. Participants donate blood and urine samples and undergo anthropometric screening, and their personal and medical histories are recorded.

Acknowledgments

The Exeter 10,000 study (EXTEND) was funded by the NIHR (UK).

Experiment summary

Samples were genotyped using an Illumina GSA chip. Analysis covariates were Principal Components 1 and 2.

Dataset ID
GWAS_EXTEND