Publication
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
Manning AK, Hivert M-F, Scott RA, et al.
Nat Genet. 2012 May 13;44(6):659-69. doi: 10.1038/ng.2274.
Phenotypes
- fasting glucose
- fasting glucose adjusted for BMI
- fasting insulin
- fasting insulin adjusted for BMI
Subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 8,372 | Atherosclerosis Risk in Communities Study (ARIC) | European |
| 857 | Baltimore Longitudinal Study of Aging (BLSA) | European |
| 2,850 | Age, Gene/Environment Susceptibility Study (AGES) | European |
| 1,183 | BSN | European |
| 1,731 | Cardiovascular Health Study (CHS) | European |
| 5,435 | Cohorte Lausanne (CoLaus) | European |
| 660 | CROAS (Vis Study) | European |
| 763 | CROATIA-Korcula (Korcula) | European |
| 460 | CROATIA-Split (Split) | European |
| 1,266 | Diabetes Genetics (DGI) | European |
| 1,070 | Erasmus Rucphen Family Study ERF) | European |
| 970 | Family Heart Study (FamHS) | European |
| 1,116 | Finland-United States Investigation of NIDDM Genetics (FUSION) | European |
| 6,479 | Framingham Heart Study (FHS) | European |
| 716 | French Adult Controls | European |
| 1,147 | Genetic Epidemiology Network of Arteriosclerosis (GENOA) | European |
| 780 | GenomEUtwin | European |
| 1,660 | Health ABC (HABC) | European |
| 2,118 | Health2000 | European |
| 1,200 | Invecchiare in Chianti (InCHIANTI) | European |
| 4,196 | NFBC1966 | European |
| 3,093 | NTR / NESDA | European |
| 664 | Orkney Complex Disease Study (ORCADES) | European |
| 4,164 | PROCARDIS | European |
| 5,974 | Rotterdam Study | European |
| 675 | Sorbs | European |
| 1,656 | SUVIMAX | European |
| 1,402 | The Fenland Study (Fenland) | European |
Project
MAGIC (the Meta-Analyses of Glucose and Insulin-related traits Consortium) represents a collaborative effort to combine data from multiple GWAS to identify additional loci that impact on glycemic and metabolic traits.
Dataset ID
GWAS_MAGIC-FGFI2012_eu