Publications
A central role for GRB10 in regulation of islet function in man.
Prokopenko I, et al.
PLoS Genet. 2014 Apr 3;10(4):e1004235. doi: 10.1371/journal.pgen.1004235
Phenotypes
- area under the curve (AUC) for insulin
- ratio of area under the curve (AUC) for insulin:AUC for glucose
- corrected insulin response
- corrected insulin response adjusted for Matsuda ISI
- disposition index
- incremental insulin at 30 min during oral glucose tolerance test
- insulin at 30 min during oral glucose tolerance test
- insulin at 30 min during oral glucose tolerance test, adjusted for BMI
- Matsuda insulin sensitivity index (ISI)
Subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 1,156 | Amish Family Diabetes Study | European |
| 1,023 | DGI | European |
| 258 | French obese adults | European |
| 1,688 | HBCS | European |
| 1,031 | RISC | European |
| 808 | Sorbs | European |
Project
MAGIC (the Meta-Analyses of Glucose and Insulin-related traits Consortium) represents a collaborative effort to combine data from multiple GWAS to identify additional loci that impact on glycemic and metabolic traits.
Dataset ID
GWAS_MAGIC-InsulinSecretionOGTT_eu