Publications
Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci.
Walford G, Gustafsson S, Rybin D, et al.
Diabetes. 2016 Oct;65(10):3200-11. doi: 10.2337/db16-0199
Phenotypes
- modified Stumvoll insulin sensitivity index (ISI) adjusted for age and sex
- modified Stumvoll insulin sensitivity index (ISI) adjusted for age, sex, and BMI
- modified Stumvoll insulin sensitivity index (ISI) adjusted for genotype-BMI interaction
Subjects
| Subjects | Cohort | Ancestry |
|---|---|---|
| 2,761 | Cardiovascular Health Study (CHS) | European |
| 462 | Finland-United States Investigation of NIDDM Genetics (FUSION) | European |
| 2,602 | Framingham Heart Study (FHS) | European |
| 962 | LURIC | European |
| 7,388 | METabolic Syndrome In Men (METSIM) | European |
| 802 | Sorbs | European |
| 962 | ULSAM | European |
Project
MAGIC (the Meta-Analyses of Glucose and Insulin-related traits Consortium) represents a collaborative effort to combine data from multiple GWAS to identify additional loci that impact on glycemic and metabolic traits.
Dataset ID
GWAS_MAGIC-ISI_eu