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AFGen exome sequence analysis

  • Read more about AFGen exome sequence analysis

Publications

Whole Exome Sequencing in Atrial Fibrillation.
Lubitz SA, et al.
PLoS Genet. 2016 Sep 2;12(9):e1006284. doi: 10.1371/journal.pgen.1006284

TOPMed HbA1c Meta-analysis WGS

  • Read more about TOPMed HbA1c Meta-analysis WGS

Publications

Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program
Sarnowski, C et al.
Am J Hum Genet. 2019 Oct 3;105(4):706-718. doi: 10.1016/j.ajhg.2019.08.010

UK Biobank CardioMetabolic Consortium CHD GWAS

  • Read more about UK Biobank CardioMetabolic Consortium CHD GWAS

Summary statistics are available for download at the CARDIoGRAMplusC4D Consortium website.

Publications

Association analyses based on false discovery rate implicate new loci for coronary artery disease.
Nelson, CP, et al.
Nat Genet. 2017 Sep;49(9):1385-1391. doi: 10.1038/ng.3913

CKDGen 1000G GWAS

  • Read more about CKDGen 1000G GWAS

Dataset

These datasets draw upon overlapping sample sets: CKDGen GWAS; CKDGen GWAS - stratified UACR associations; and CKDGen GWAS - stratified serum creatinine associations.

Download summary statistics

Publications

1000 Genomes-based meta-analysis identifies 10 novel loci for kidney function.
Gorski M, et al.
Sci Rep. 2017 Apr 28;7:45040. doi: 10.1038/srep45040

CKDGen GWAS - microalbuminuria associations

  • Read more about CKDGen GWAS - microalbuminuria associations

Dataset

All CKDGen GWAS datasets draw upon overlapping sample sets.

Download summary statistics

Publications

Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.
Teumer A, et al.
Nat Commun. 2019 Sep 11;10(1):4130. doi: 10.1038/s41467-019-11576-0

Joint T2D-CHD GWAS

  • Read more about Joint T2D-CHD GWAS

Dataset

Download summary statistics for T2D meta-analysis

Download summary statistics for bivariate analysis

GoT2D WGS + replication

  • Read more about GoT2D WGS + replication

Dataset

All samples in this dataset are included in the "DIAMANTE (European) T2D GWAS" dataset.

Publications

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, et al.
Sci Data. 2017 Dec 19;4:170179. doi: 10.1038/sdata.2017.179

GoT2D WGS

  • Read more about GoT2D WGS

Dataset

Most samples in this dataset are included in the "DIAMANTE (European) T2D GWAS" dataset.

Publications

Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.
Flannick J, Fuchsberger C, Mahajan A, et al.
Sci Data. 2017 Dec 19;4:170179. doi: 10.1038/sdata.2017.179

UK Biobank eBMD and fracture GWAS

  • Read more about UK Biobank eBMD and fracture GWAS

Dataset

Download summary statistics

Publications

An atlas of genetic influences on osteoporosis in humans and mice.
Morris JA, et al.
Nat Genet. 2019 Feb;51(2):258-266. doi: 10.1038/s41588-018-0302-x

SUMMIT Diabetic Kidney Disease GWAS: subjects with T1D or T2D, ESRD vs. controls

  • Read more about SUMMIT Diabetic Kidney Disease GWAS: subjects with T1D or T2D, ESRD vs. controls

Summary statistics are available for download from the GWAS Catalog.

Publications

A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.
van Zuydam NR, et al.
Diabetes. 2018 Jul;67(7):1414-1427. doi: 10.2337/db17-0914

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